Dario Strina

Research Technician

Area of interest:

I work at IRGB Milan Unit as Senior Technician. 

My expertise are in molecular biology techniques, mouse surgery and cell culture including murine and human induced pluripotent stem cells. 

In particular, in the last years I have been involved in the study of human bone diseases in mouse models. I have optimized mouse micro surgery including in utero transplantation, femoral  bone injections, and ovariectomy . In parallel I am an expert in the manipulation of human and mouse induced pluripotent stem cell (iPSC cells line), subcloning of single iPSC clone, iPSC characterization and differentiation 

Laboratory management is also one of my duties at IRGB Milan Unit

Most significant publications:


Palagano, E; Muggeo, S; Crisafulli, L; Tourkova, I L; Strina, D; Mantero, S; Fontana, E; Locatelli, S L; Monari, M; Morenghi, E; Carlo-Stella, C; Barnett, J B; Blair, H C; Vezzoni, P; Villa, A; Sobacchi, C; Ficara, F

Generation of an immunodeficient mouse model of tcirg1-deficient autosomal recessive osteopetrosis Journal Article

In: Bone Rep, 12 , pp. 100242, 2020.


Ritelli, M; Palagano, E; Cinquina, V; Beccagutti, F; Chiarelli, N; Strina, D; Hall, I F; Villa, A; Sobacchi, C; Colombi, M

Genome-first approach for the characterization of a complex phenotype with combined NBAS and CUL4B deficiency Journal Article

In: Bone, 140 , pp. 115571, 2020.



Castelli, A; Susani, L; Menale, C; Muggeo, S; Caldana, E; Strina, D; Cassani, B; Recordati, C; Scanziani, E; Ficara, F; Villa, A; Vezzoni, P; Paulis, M

Chromosome Ŧransplantation: Correction of the Chronic Granulomatous Đisease Đefect in Mouse Induced Pluripotent Stem Cells Journal Article

In: Stem Cells, 37 (7), pp. 876–887, 2019.


Menale, C; Robinson, L J; Palagano, E; Rigoni, R; Erreni, M; Almarza, A J; Strina, D; Mantero, S; Lizier, M; Forlino, A; Besio, R; Monari, M; Vezzoni, P; Cassani, B; Blair, H C; Villa, A; Sobacchi, C

Absence of Đipeptidyl Peptidase 3 Increases Oxidative Stress and Causes Bone Loss Journal Article

In: J Bone Miner Res, 34 (11), pp. 2133–2148, 2019.



Sobacchi, C; Erreni, M; Strina, D; Palagano, E; Villa, A; Menale, C

3Đ Bone Biomimetic Scaffolds for Basic and Ŧranslational Studies with Mesenchymal Stem Cells Journal Article

In: Int J Mol Sci, 19 (10), 2018.


  • Via Manzoni 113, 20089, Rozzano (Milan), Italy – c/o Humanitas Research Hospital

  • dario.strina@irgb.cnr.it

  • +39 02 82245162