Laura Frogheri


Area of interest:

Laura Frogheri graduated in Biological Sciences at University of Sassari. She works as researcher in the CNR since 1990. Since graduation her research activity was related to molecular biology of congenital and acquired blood pathologies, in particular thalassemiashemoglobinopathies, and myelodysplastic syndromes.  

Starting in 2010, her interest focused on molecular bases of thyroid neoplasm, specifically on the Familial form of Medullary Thyroid Carcinoma (FMTC or Inherited Medullary Carcinoma), a rare thyroid cancer due to RET proto-oncogene mutations. The goal of the research was to identify genetic modifiers in regulator genes of RETsignaling pathway, that could explain some variations in phenotypes among FMTC affected patients 

Currently her research activity is based on cancer genetics with particular attention to pancreatic cancer by using Next Generation Sequencing (NGS) technologies with multigene panel, aimed to identify novel tumor biomarkers for the development of targeted therapies.

Most significant publications:


Köttgen, Anna; Albrecht, Eva; Teumer, Alexander; Vitart, Veronique; Krumsiek, Jan; Hundertmark, Claudia; Pistis, Giorgio; Ruggiero, Daniela; ...,; Tore, Silvia; ...,; Ripatti, Samuli; Soranzo, Nicole; Toniolo, Daniela; Chasman, Daniel I; Raitakari, Olli; Kao, W H Linda; Ciullo, Marina; Fox, Caroline S; Caulfield, Mark; Bochud, Murielle; Gieger, Christian

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations Journal Article

In: Nature Genetics, 45 (2), pp. 145–154, 2013, ISSN: 1546-1718.

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