Maria Franca Marongiu


Area of interest:

Conducting experiments on appropriate animal models for performing functional studies on specific genetic variants involved in the development of autoimmune diseases. Phenotypic and genotypic characterization of transgenic, knockout and knockin mouse lines. Flow cytometric analysis of cell subpopulations.In vivo studies of malaria-related gene variants. Techniques of infection and analysis of murine malaria parasite Plasmodium berghei.

Most significant publications:


Marongiu, Maria F; Porcu, Susanna; Poddie, Daniela; Drabek, Dubravka; Wit, Ton De; Cao, Antonio; Ristaldi, Maria S

Different switching patterns of β-thalassaemic mutations at the proximal and distal CACCC box of the human HBB (β-globin) gene Journal Article

In: British Journal of Haematology, 173 (5), pp. 794–797, 2016, ISSN: 1365-2141.

Links | BibTeX


Durlak, Marta; Fugazza, Cristina; Elangovan, Sudharshan; Marini, Maria Giuseppina; Marongiu, Maria Franca; Moi, Paolo; Fraietta, Ivan; Cappella, Paolo; Barbarani, Gloria; Font-Monclus, Isaura; Mauri, Mario; Ottolenghi, Sergio; Gasparri, Fabio; Ronchi, Antonella

A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds Journal Article

In: PloS One, 10 (10), pp. e0141083, 2015, ISSN: 1932-6203.

Abstract | Links | BibTeX


Manchinu, Maria F; Marongiu, Maria F; Poddie, Daniela; Casu, Carla; Latini, Veronica; Simbula, Michela; Galanello, Renzo; Moi, Paolo; Cao, Antonio; Porcu, Susanna; Ristaldi, Maria S

In vivo activation of the human δ-globin gene: the therapeutic potential in β-thalassemic mice Journal Article

In: Haematologica, 99 (1), pp. 76–84, 2014, ISSN: 1592-8721.

Abstract | Links | BibTeX


Ramos, Pedro; Casu, Carla; Gardenghi, Sara; Breda, Laura; Crielaard, Bart J; Guy, Ella; Marongiu, Maria Franca; Gupta, Ritama; Levine, Ross L; Abdel-Wahab, Omar; Ebert, Benjamin L; Rooijen, Nico Van; Ghaffari, Saghi; Grady, Robert W; Giardina, Patricia J; Rivella, Stefano

Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia Journal Article

In: Nature Medicine, 19 (4), pp. 437–445, 2013, ISSN: 1546-170X.

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Marongiu, Maria Franca; Poddie, Daniela; Porcu, Susanna; Manchinu, Maria Francesca; Castelli, Maria Paola; Sogos, Valeria; Bini, Valentina; Frau, Roberto; Caredda, Elisabetta; Collu, Maria; Ristaldi, Maria Serafina

Reversible disruption of pre-pulse inhibition in hypomorphic-inducible and reversible CB1-/- mice Journal Article

In: PloS One, 7 (4), pp. e35013, 2012, ISSN: 1932-6203.

Abstract | Links | BibTeX