Grazia Palomba

Researcher

Temporary assigned to IRGB from Biomolecular Chemistry Institute (ICB) CNR

Area of interest:

Educational background – G. Palomba graduated in Chemistry and PhD in Biochemistry, Biology and Molecular Biotechnology at the University of Sassari. 

Position held – At present she works as researcher in the CNR since 2008.    

Research activity – Identification and characterization of molecular genetic alterations in candidate genes involved in solid tumor pathogenesis with particular focus on colon rectal cancer, breast and ovarian cancer. 

Especially,  her research involve clinical-translational and basic research, molecular diagnostics in support of personalized therapy for patients. 

Expertise in sequencing and NGS analyses with multigene panel of tumor samples. 

 

 

Most significant publications:

2024

Veroni, C.; Olla, S.; Brignone, M. S.; Siguri, C.; Formato, A.; Marra, M.; Manzoli, R.; Macario, M. C.; Ambrosini, E.; Moro, E.; Agresti, C.

The Antioxidant Drug Edaravone Binds to the Aryl Hydrocarbon Receptor (AHR) and Promotes the Downstream Signaling Pathway Activation Journal Article

In: Biomolecules, 14 (4), 2024, ([PubMed Central:hrefhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948512PMC2948512] [DOI:hrefhttps://dx.doi.org/10.1371/journal.pone.001312810.1371/journal.pone.0013128] [PubMed:hrefhttps://www.ncbi.nlm.nih.gov/pubmed/2095704620957046]).

Abstract | BibTeX

2022

Mariani, Stefano; Puzzoni, Marco; Giampieri, Riccardo; Ziranu, Pina; Pusceddu, Valeria; Donisi, Clelia; Persano, Mara; Pinna, Giovanna; Cimbro, Erika; Parrino, Alissa; Spanu, Dario; Pretta, Andrea; Lai, Eleonora; Liscia, Nicole; Lupi, Alessio; Giglio, Enrica; Palomba, Grazia; Casula, Milena; Pisano, Marina; Palmieri, Giuseppe; Scartozzi, Mario

Liquid Biopsy-Driven Cetuximab Rechallenge Strategy in Molecularly Selected Metastatic Colorectal Cancer Patients Journal Article

In: Frontiers in Oncology, 12 (852583), 2022.

Abstract | BibTeX

Paliogiannis, Panagiotis; Colombino, Maria; Sini, Maria Cristina; Manca, Antonella; Casula, Milena; Palomba, Grazia; Pisano, Marina; Doneddu, Valentina; Zinellu, Angelo; Santeufemia, Davide; and Giovanni Sotgiu,; Cossu, Antonio; Palmieri, Giuseppe

Global prognostic impact of driver genetic alterations in patients with lung adenocarcinoma: a real-life study Journal Article

In: BMC Pulm Med, 22 (1), pp. 32, 2022, ISSN: 1471-2466.

Abstract | Links | BibTeX

2021

Palomba, Grazia; Paliogiannis, Panagiotis; Sini, Maria C; Colombino, Maria; Casula, Milena; Manca, Antonella; Pisano, Marina; Sotgiu, Giovanni; Doneddu, Valentina; Palmieri, Giuseppe; Cossu, Antonio

KIT and PDGFRa mutational patterns in Sardinian patients with gastrointestinal stromal tumors Journal Article

In: Eur J Cancer Prev, 30 (1), pp. 53–58, 2021, ISSN: 1473-5709.

Abstract | Links | BibTeX

2020

Colombino, M.; Rozzo, C.; Paliogiannis, P.; Casula, M.; Manca, A.; Doneddu, V.; Fedeli, M. A.; Sini, M. C.; Palomba, G.; Pisano, M.; Ascierto, P. A.; Caracò, C.; Lissia, A.; Cossu, A.; Palmieri, G.

Comparison of BRAF Mutation Screening Strategies in a Large Real-Life Series of Advanced Melanoma Patients Journal Article

In: J Clin Med, 9 (8), 2020.

Abstract | BibTeX