A new international collaborative study involving the NeuroWES Consortium, with the contribution of the research team led by Andrea Angius at the CNR-Istituto di Ricerca Genetica e Biomedica (IRGB), has provided important insights into the genetic basis of neurodevelopmental disorders through the analysis of one of the largest Italian cohorts investigated by exome sequencing [...]
A recent study led by researchers from the Institute for Genetic and Biomedical Research of the National Research Council (CNR‑IRGB), in collaboration with the University of Sassari, has identified a novel genomic signature capable of improving survival prediction in patients with colorectal cancer. The article, published in Oncology Research as “Seven-Gene Signature and [...]
A new collaborative international genetic study led by Prof. Mauro D’Amato from the CIC bioGUNE in Spain and LUM University in Italy, with contributions from the research group of Dr. Serena Sanna at CNR‑IRGB, has identified genetic factors that link irritable bowel syndrome to lipid metabolism and triglyceride regulation. The study was Published [...]
A study conducted by the Institute for Genetic and Biomedical Research of the National Research Council (CNR‑IRGB), in collaboration with the IRCCS Burlo Garofolo in Trieste, has revealed that healthy Italian women display a vaginal microbiota composition that differs markedly from that of women in Northern Europe. The research, published in mSystems, analysed [...]
A new collaborative international genetic study led by Prof. Mauro D’Amato from the CIC bioGUNE in Spain and LUM University in Italy, with contributions from the research group of Dr. Serena Sanna at CNR‑IRGB, has identified genetic factors that influence bowel movement frequency. The study was Published in Gut, the research analysed data from [...]
Online il catalogo “Il Cnr è a scuola”, che raccoglie una selezione delle iniziative divulgative ed educative al momento attive in tutta Italia, destinate a vari ordini e gradi di scuole per l’anno scolastico in corso e per l’anno scolastico 2024-2025. Il catalogo verra’ presentato a Firenze il 20 Marzo con Didacta Italia, il [...]
Lung-to-Heart Nano-in-Micro Peptide Promotes Cardiac Recovery in a Pig Model of Chronic Heart Failure In this study, the authors sought to assess tolerability and efficacy of an inhalable lung-to-heart nano-in-micro technology (LungToHeartNIM) for cardiac-specific targeting of a mimetic peptide (MP), a first-in-class for modulating impaired L-type calcium channel (LTCC) trafficking, in a clinically relevant [...]
07/11/2023 Double recognition for Serena Sanna, Research Director at the Institute for Genetic and Biomedical Research (Cnr-Irgb) in Cagliari: on Monday, November 13 in Rome, at the Protomoteca Hall of the Capitoline Hill, she receives the “Marcello Sgarlata Research Award”. The prize is granted, upon nomination by the President of the CNR, to outstanding [...]
In this study, we evaluated the predictive and prognostic role of HER2 protein/gene expression levels in combination with clinicopathologic features in patients who received neoadjuvant trastuzumab-based chemotherapy. The tumor pathologic complete response (pCR) rate was 40.9%, and the mortality rate was lower than in subjects with a lower response. A better pCR rate correlated [...]
In a new study, a group of researchers from the University of Groningen who have joined forces as the Groningen Microbiome Team have shown that your genes influence the composition of your gut microbiome. Dr. Serena Sanna, now Director of Research at the IRGB-CNR Institute has coordinated this study together with Prof. Alexandra Zhernakova. The results [...]