ERC Starting Grant 2022 awarded to Serena Sanna at the IRGB

2023-01-26T13:15:23+00:00January 26th, 2023|home, News|

"SEMICYCLE" the project conceived by Serena Sanna, of the Institute of genetic and biomedical research (Irgb) of the National Research Council of Cagliari, was funded under the Starting Grants 2022 program of the European Research Council (ERC) for a total of 1.5 million euros. The project is aimed at understanding the interactions between female [...]

The hidden gene-microbes communication

2023-01-24T14:54:58+00:00February 4th, 2022|home, News|

In a new study, a group of researchers from the University of Groningen who have joined forces as the Groningen Microbiome Team have shown that your genes influence the composition of your gut microbiome. Dr. Serena Sanna, now Director of Research at the IRGB-CNR Institute has coordinated this study together with Prof. Alexandra Zhernakova. The results [...]

Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids.

2021-01-21T14:39:18+00:00January 18th, 2021|home, News|

A study published in the Nature Communications journal propose an MR method, MR-link, that accounts for unobserved pleiotropy and LD by leveraging information from individual-level data, even when only one eQTL variant is present. Inference of causality between gene expression and complex traits using Mendelian randomization (MR) is confounded by pleiotropy and linkage [...]

Genomic history of the Sardinian population

2018-12-20T15:27:00+00:00September 17th, 2018|News|

The population of the Mediterranean island of Sardinia has made important contributions to genome-wide association studies of complex disease traits and, based on ancient DNA studies of mainland Europe, Sardinia is hypothesized to be a unique refuge for early Neolithic ancestry. To provide new insights on the genetic history of this flagship population, we analyzed [...]


2018-12-20T17:23:40+00:00June 18th, 2018|home, News|

LinDA is a tool that, for a given variant, determines all the variants in Linkage Disequilibrium and whether they intersect with other association studies. A large manually curated collection of QTL and association studies can be easily interrogated and results are displayed with interactive plots and tables. LinDA offers also complementary tools, such as [...]

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