ERC Starting Grant 2022 awarded to Serena Sanna at the IRGB

2023-01-26T13:15:23+00:00January 26th, 2023|home, News|

"SEMICYCLE" the project conceived by Serena Sanna, of the Institute of genetic and biomedical research (Irgb) of the National Research Council of Cagliari, was funded under the Starting Grants 2022 program of the European Research Council (ERC) for a total of 1.5 million euros. The project is aimed at understanding the interactions between female [...]

The hidden gene-microbes communication

2023-01-24T14:54:58+00:00February 4th, 2022|home, News|

In a new study, a group of researchers from the University of Groningen who have joined forces as the Groningen Microbiome Team have shown that your genes influence the composition of your gut microbiome. Dr. Serena Sanna, now Director of Research at the IRGB-CNR Institute has coordinated this study together with Prof. Alexandra Zhernakova. The results [...]

Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids.

2021-01-21T14:39:18+00:00January 18th, 2021|home, News|

A study published in the Nature Communications journal propose an MR method, MR-link, that accounts for unobserved pleiotropy and LD by leveraging information from individual-level data, even when only one eQTL variant is present. Inference of causality between gene expression and complex traits using Mendelian randomization (MR) is confounded by pleiotropy and linkage [...]


2018-12-20T17:23:40+00:00June 18th, 2018|home, News|

LinDA is a tool that, for a given variant, determines all the variants in Linkage Disequilibrium and whether they intersect with other association studies. A large manually curated collection of QTL and association studies can be easily interrogated and results are displayed with interactive plots and tables. LinDA offers also complementary tools, such as [...]

Discovery of a gene variant that confers risk of multiple sclerosis and lupus

2018-12-20T11:34:34+00:00April 27th, 2017|home, News|

A study published in the New England Journal of Medicine reports an important new mechanism of predisposition to two autoimmune diseases, multiple sclerosis (MS) and systemic lupus erythematosus (Lupus). The study, supported by the Italian Multiple Sclerosis Foundation (FISM) and the National Institute on Aging of the NIH, was carried out by an international team [...]

New genes linked to short – stature, risk factors for heart disease, and hemoglobin levels regulation

2018-12-20T11:51:54+00:00November 11th, 2015|home, News|

A team of international researchers from the SardiNIA/ProgeNIA study, have discovered new genes associated with height, risk factors for heart disease, and regulation of hemoglobin levels, using advanced whole-genome sequencing technology. Findings detected in general population individuals from 4 Sardinian villages assessed in the SardiNIA cohort study are presented in a series of papers in [...]

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