Genetic study links gut motility to vitamin B1

A new collaborative international genetic study led by Prof. Mauro D’Amato from the CIC bioGUNE in Spain and LUM University in Italy, with contributions from the research group of Dr. Serena Sanna at CNR‑IRGB, has identified genetic factors that influence bowel movement frequency. The study was  Published in Gut, [...]

Lung-to-Heart Nano-in-Micro Peptide Promotes Cardiac Recovery in a Pig Model of Chronic Heart Failure

Lung-to-Heart Nano-in-Micro Peptide Promotes Cardiac Recovery in a Pig Model of Chronic Heart Failure In this study, the authors sought to assess tolerability and efficacy of an inhalable lung-to-heart nano-in-micro technology (LungToHeartNIM) for cardiac-specific targeting of a mimetic peptide (MP), a first-in-class for modulating impaired L-type calcium channel (LTCC) [...]

Double recognition for Serena Sanna, Head of Research

07/11/2023 Doppio riconoscimento per Serena Sanna, dirigente di ricerca dell'Istituto di ricerca genetica e biomedica (Cnr-Irgb) di Cagliari: lunedì 13 novembre a Roma, presso la protomoteca del Campidoglio, ritira il “Premio alla ricerca Marcello Sgarlata”. Il premio è affidato, su designazione della Presidente del Cnr, a eccellenti ricercatori e ricercatrici che [...]

Biomarker dynamics affecting neoadjuvant therapy response and outcome of HER2-positive breast cancer subtype

In this study, we evaluated the predictive and prognostic role of HER2 protein/gene expression levels in combination with clinicopathologic features in patients who received neoadjuvant trastuzumab-based chemotherapy. The tumor pathologic complete response (pCR) rate was 40.9%, and the mortality rate was lower than in subjects with a lower response. [...]

ERC Starting Grant 2022 awarded to Serena Sanna at the IRGB

"SEMICYCLE" the project conceived by Serena Sanna, of the Institute of genetic and biomedical research (Irgb) of the National Research Council of Cagliari, was funded under the Starting Grants 2022 program of the European Research Council (ERC) for a total of 1.5 million euros. The project is aimed at [...]