A study conducted by the Institute for Genetic and Biomedical Research of the National Research Council (CNR‑IRGB), in collaboration with the IRCCS Burlo Garofolo in Trieste, has revealed that healthy Italian women display a vaginal microbiota composition that differs markedly from that of women in Northern Europe. The research, published in mSystems, analysed 61 [...]
A new collaborative international genetic study led by Prof. Mauro D’Amato from the CIC bioGUNE in Spain and LUM University in Italy, with contributions from the research group of Dr. Serena Sanna at CNR‑IRGB, has identified genetic factors that influence bowel movement frequency. The study was Published in Gut, the research analysed data from [...]
Online il catalogo “Il Cnr è a scuola”, che raccoglie una selezione delle iniziative divulgative ed educative al momento attive in tutta Italia, destinate a vari ordini e gradi di scuole per l’anno scolastico in corso e per l’anno scolastico 2024-2025. Il catalogo verra’ presentato a Firenze il 20 Marzo con Didacta Italia, il [...]
Lung-to-Heart Nano-in-Micro Peptide Promotes Cardiac Recovery in a Pig Model of Chronic Heart Failure In this study, the authors sought to assess tolerability and efficacy of an inhalable lung-to-heart nano-in-micro technology (LungToHeartNIM) for cardiac-specific targeting of a mimetic peptide (MP), a first-in-class for modulating impaired L-type calcium channel (LTCC) trafficking, in a clinically relevant [...]
07/11/2023 Doppio riconoscimento per Serena Sanna, dirigente di ricerca dell'Istituto di ricerca genetica e biomedica (Cnr-Irgb) di Cagliari: lunedì 13 novembre a Roma, presso la protomoteca del Campidoglio, ritira il “Premio alla ricerca Marcello Sgarlata”. Il premio è affidato, su designazione della Presidente del Cnr, a eccellenti ricercatori e ricercatrici che si sono distinti per “il [...]
In this study, we evaluated the predictive and prognostic role of HER2 protein/gene expression levels in combination with clinicopathologic features in patients who received neoadjuvant trastuzumab-based chemotherapy. The tumor pathologic complete response (pCR) rate was 40.9%, and the mortality rate was lower than in subjects with a lower response. A better pCR rate correlated [...]
In a new study, a group of researchers from the University of Groningen who have joined forces as the Groningen Microbiome Team have shown that your genes influence the composition of your gut microbiome. Dr. Serena Sanna, now Director of Research at the IRGB-CNR Institute has coordinated this study together with Prof. Alexandra Zhernakova. The results [...]
A grant recently approved will evaluate a possible approach to the treatment of β-hemoglobinopathies based on the enhancement of HbA2 expression. […]
A study recently published in British Journal of Haematology described a novel missense mutation (p.Pro27Ser) in the GP1BB gene associated with platelets count reduction. […]
The only cure for celiac disease is lifelong adherence to a strict gluten-free diet. IRGB Researchers and collaborators of the University of Groningen have identified a master regulator gene that is a potential drug target for an alternative cure. […]